Product Data Sheet
123B9
Catalog No. A84697
123B9 is a potent and selective agonist of the EphA2 receptor, exhibiting a Kd value of 4.0 μM. This compound selectively binds to the ligand-binding domain of the EphA2 tyrosine kinase receptor, facilitating downstream signaling pathways. Importantly, 123B9 does not significantly affect the ligand-binding domains of the closely related EphA3 and EphA4 receptors, making it a valuable tool for targeted studies in cancer research and therapeutic applications involving EphA2 signaling.
Chemical Information
| Catalog Num | A84697 |
|---|---|
| M. Wt | 1321.79 |
| Formula | C58H82ClFN12O20 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2225868-19-7 |
| Synonyms | |
| SMILES | C([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC(COC2=CC(Cl)=C(F)C=C2)=O)CO)=O)C)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CO)=O)CCO)=O)CCCC)=O)CCC4)[C@@H](C)C)=O)CO)=O)CC(O)=O)=O)CCC3 |
Biological Activity
| Description | 123B9 is a potent and selective agonist of the EphA2 receptor, exhibiting a Kd value of 4.0 μM. This compound selectively binds to the ligand-binding domain of the EphA2 tyrosine kinase receptor, facilitating downstream signaling pathways. Importantly, 123B9 does not significantly affect the ligand-binding domains of the closely related EphA3 and EphA4 receptors, making it a valuable tool for targeted studies in cancer research and therapeutic applications involving EphA2 signaling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
