Product Data Sheet
ER-27319 maleate
Catalog No. A84729
ER-27319 maleate is a selective inhibitor of spleen tyrosine kinase (SYK), effectively blocking its tyrosine phosphorylation and subsequent activity. This compound demonstrates significant biological activity by inhibiting the release of antigen-induced allergic mediators from both human and rat mast cells, with an IC50 value of 10 μM. ER-27319 maleate is valuable for research in allergic diseases and inflammation pathways.
Chemical Information
| Catalog Num | A84729 |
|---|---|
| M. Wt | 396.44 |
| Formula | C22H24N2O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1204480-26-1 |
| Synonyms | |
| SMILES | O=C1C2=C(C=CC=C2)N(CCCN)C3=C(C)C(C)=CC=C13.O=C(O)/C=C\C(O)=O |
Biological Activity
| Description | ER-27319 maleate is a selective inhibitor of spleen tyrosine kinase (SYK), effectively blocking its tyrosine phosphorylation and subsequent activity. This compound demonstrates significant biological activity by inhibiting the release of antigen-induced allergic mediators from both human and rat mast cells, with an IC50 value of 10 μM. ER-27319 maleate is valuable for research in allergic diseases and inflammation pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
