Product Data Sheet
(rel)-PRT062607
Catalog No. A84738
(rel)-PRT062607 is a selective inhibitor of Syk kinase, demonstrating high potency with an IC50 value of 1-2 nM. This compound exhibits over 80-fold selectivity against related kinases such as Fgr, Lyn, FAK, Pyk2, and Zap70. Its specificity makes it a valuable tool for studying Syk-mediated pathways in various biological contexts and offers potential applications in autoimmune and inflammatory disease research.
Chemical Information
| Catalog Num | A84738 |
|---|---|
| M. Wt | 393.45 |
| Formula | C19H23N9O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1194954-52-3 |
| Synonyms | (rel)-P505-15; (rel)-PRT-2607; (rel)-BIIB-057 |
| SMILES | NC(C(C(NC1=CC(N2N=CC=N2)=CC=C1)=N3)=CN=C3N[C@H]4[C@H](CCCC4)N)=O |
Biological Activity
| Description | (rel)-PRT062607 is a selective inhibitor of Syk kinase, demonstrating high potency with an IC50 value of 1-2 nM. This compound exhibits over 80-fold selectivity against related kinases such as Fgr, Lyn, FAK, Pyk2, and Zap70. Its specificity makes it a valuable tool for studying Syk-mediated pathways in various biological contexts and offers potential applications in autoimmune and inflammatory disease research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
