Product Data Sheet
BI1002494
Catalog No. A84742
BI1002494 is a selective inhibitor of spleen tyrosine kinase (SYK) with oral bioavailability. It demonstrates potent inhibitory activity with an IC50 of 115 nM against high-affinity IgE receptor-mediated degranulation in mast cells and basophils. This compound is a valuable tool for studying immune responses and can be applied in a variety of immunology research applications.
Chemical Information
| Catalog Num | A84742 |
|---|---|
| M. Wt | 423.46 |
| Formula | C23H25N3O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1319738-39-0 |
| Synonyms | |
| SMILES | O=C1NC[C@@H](C1)[C@@H](C)OC2=C3C=CC=NC3=CC(C4=CC(OC)=C(C(OC)=C4)OC)=N2 |
Biological Activity
| Description | BI1002494 is a selective inhibitor of spleen tyrosine kinase (SYK) with oral bioavailability. It demonstrates potent inhibitory activity with an IC50 of 115 nM against high-affinity IgE receptor-mediated degranulation in mast cells and basophils. This compound is a valuable tool for studying immune responses and can be applied in a variety of immunology research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
