Product Data Sheet
AZ14145845
Catalog No. A84752
AZ14145845 is a selective inhibitor targeting the TAM receptor kinases Mer and Axl, classified as a type I1/2 dual kinase inhibitor. This compound demonstrates notable in vivo efficacy, making it a valuable tool for research in cancer biology and therapeutic resistance mechanisms. Its selective inhibition of the TAM receptors contributes to the modulation of immune responses and potential enhancement of antitumor activity, serving as a significant asset in studies focused on cancer treatment and immunotherapy.
Chemical Information
| Catalog Num | A84752 |
|---|---|
| M. Wt | 561.68 |
| Formula | C32H35N9O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2830555-70-7 |
| Synonyms | |
| SMILES | CC1=C(C2=CN=C(C3=NN=C(N(CC4=CN5C(C=C4)=NC=C5C6=CC=C(CN(C)C)C=C6)C)O3)C(C)=C2)C(C)=NN1C |
Biological Activity
| Description | AZ14145845 is a selective inhibitor targeting the TAM receptor kinases Mer and Axl, classified as a type I1/2 dual kinase inhibitor. This compound demonstrates notable in vivo efficacy, making it a valuable tool for research in cancer biology and therapeutic resistance mechanisms. Its selective inhibition of the TAM receptors contributes to the modulation of immune responses and potential enhancement of antitumor activity, serving as a significant asset in studies focused on cancer treatment and immunotherapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
