Product Data Sheet
Anticancer agent 109
Catalog No. A84768
Anticancer agent 109 is a Gas6/Axl inhibitor that demonstrates significant anti-cancer activity. This compound effectively downregulates the expression of Gas6 and Axl, which in turn reduces the activation of p-PI3K and p-AKT in cancer cells. Anticancer agent 109 induces G1 phase cell cycle arrest and promotes apoptosis, leading to substantial inhibition of tumor growth in nude mouse models. This reagent is suitable for research focused on cancer biology and therapeutic development targeting the Gas6/Axl signaling pathway.
Chemical Information
| Catalog Num | A84768 |
|---|---|
| M. Wt | 317.34 |
| Formula | C19H15N3O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2097497-16-8 |
| Synonyms | |
| SMILES | O=C(/C(C1=C2C)=C\C3=NC4=C(C=CC=C4)C=C3)NC1=NC(C)=C2O |
Biological Activity
| Description | Anticancer agent 109 is a Gas6/Axl inhibitor that demonstrates significant anti-cancer activity. This compound effectively downregulates the expression of Gas6 and Axl, which in turn reduces the activation of p-PI3K and p-AKT in cancer cells. Anticancer agent 109 induces G1 phase cell cycle arrest and promotes apoptosis, leading to substantial inhibition of tumor growth in nude mouse models. This reagent is suitable for research focused on cancer biology and therapeutic development targeting the Gas6/Axl signaling pathway. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
