Product Data Sheet
Tie2 kinase inhibitor 3
Catalog No. A84781
Tie2 Kinase Inhibitor 3 is a potent inhibitor of the Tie-2 kinase, exhibiting an IC50 value of 30 nM. By competing with the ATP binding site of Tie-2, this compound effectively inhibits phosphorylation and signaling pathways associated with Tie-2, thereby influencing the stability and maturation of blood vessels. Its mechanisms provide valuable insights into tumor angiogenesis, making Tie2 kinase inhibitor 3 a significant tool for research focused on restricting tumor growth and modulating angiogenic processes.
Chemical Information
| Catalog Num | A84781 |
|---|---|
| M. Wt | 598.59 |
| Formula | C29H30F4N8O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 870225-11-9 |
| Synonyms | |
| SMILES | O=C(C1=CC(OC2=C(C3=NC(NC)=NC=N3)C=CC=N2)=CC=C1F)NC4=CC(C(F)(F)F)=CC=C4N(CCCN(C)C)C |
Biological Activity
| Description | Tie2 Kinase Inhibitor 3 is a potent inhibitor of the Tie-2 kinase, exhibiting an IC50 value of 30 nM. By competing with the ATP binding site of Tie-2, this compound effectively inhibits phosphorylation and signaling pathways associated with Tie-2, thereby influencing the stability and maturation of blood vessels. Its mechanisms provide valuable insights into tumor angiogenesis, making Tie2 kinase inhibitor 3 a significant tool for research focused on restricting tumor growth and modulating angiogenic processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
