Product Data Sheet
BSF-466895
Catalog No. A84782
BSF-466895 is a potent Tie2 inhibitor with an IC50 value of 5 nM, demonstrating significant inhibition of Tie1 as well. This compound is valuable for research applications focused on vascular biology and angiogenesis, as well as exploring the therapeutic potential in disorders related to angiogenic dysregulation. BSF-466895 serves as a useful tool for elucidating the role of the Tie2 signaling pathway in various biological contexts.
Chemical Information
| Catalog Num | A84782 |
|---|---|
| M. Wt | 632.58 |
| Formula | C29H32Cl2FN7O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 262442-90-0 |
| Synonyms | A-422885.66 |
| SMILES | O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN([C@H]4CC[C@H](N5CCN(C)CC5)CC4)C6=NC=NC(N)=C63)C=C2F)=O |
Biological Activity
| Description | BSF-466895 is a potent Tie2 inhibitor with an IC50 value of 5 nM, demonstrating significant inhibition of Tie1 as well. This compound is valuable for research applications focused on vascular biology and angiogenesis, as well as exploring the therapeutic potential in disorders related to angiogenic dysregulation. BSF-466895 serves as a useful tool for elucidating the role of the Tie2 signaling pathway in various biological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
