Product Data Sheet
BRD2577
Catalog No. A84787
BRD2577 is a selective inhibitor of mercaptopyruvate sulfurtransferase (3-MST) with an IC50 value of 9.9 μM. This compound effectively reduces hydrogen sulfide (H2S) production in colon carcinoma cells, providing insights into the metabolic pathways associated with this cancer type. While BRD2577 shows minimal impact on colon cancer cell proliferation and mitochondrial function, it serves as a valuable tool for investigating the role of H2S in colon cancer biology and therapeutic strategies.
Chemical Information
| Catalog Num | A84787 |
|---|---|
| M. Wt | 317.36 |
| Formula | C15H15N3O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 353781-42-7 |
| Synonyms | |
| SMILES | O=C1N=C(SCC(=O)C2=CC=C(C=C2)NC(=O)C)NC(=C1)C |
Biological Activity
| Description | BRD2577 is a selective inhibitor of mercaptopyruvate sulfurtransferase (3-MST) with an IC50 value of 9.9 μM. This compound effectively reduces hydrogen sulfide (H2S) production in colon carcinoma cells, providing insights into the metabolic pathways associated with this cancer type. While BRD2577 shows minimal impact on colon cancer cell proliferation and mitochondrial function, it serves as a valuable tool for investigating the role of H2S in colon cancer biology and therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
