Product Data Sheet
MR24
Catalog No. A84789
MR24 is a selective inhibitor of mammalian STE20-like kinases MST3 and MST4. It demonstrates an EC50 of 57 nM for MST3 and 583 nM for MST4, highlighting its targeted activity. MR24 induces G1 phase cell cycle arrest, making it a valuable tool for investigating cell cycle regulation. This compound is particularly relevant for cancer research, including studies focused on breast, liver, and lung cancers.
Chemical Information
| Catalog Num | A84789 |
|---|---|
| M. Wt | 509.00 |
| Formula | C26H29ClN6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3056814-89-9 |
| Synonyms | |
| SMILES | CC1=CC=CC(C2=CC(Cl)=C(C=C2)C3=CC4=C(N(C3=O)CCCCN)N=C(N=C4)NC(CO)CO)=N1 |
Biological Activity
| Description | MR24 is a selective inhibitor of mammalian STE20-like kinases MST3 and MST4. It demonstrates an EC50 of 57 nM for MST3 and 583 nM for MST4, highlighting its targeted activity. MR24 induces G1 phase cell cycle arrest, making it a valuable tool for investigating cell cycle regulation. This compound is particularly relevant for cancer research, including studies focused on breast, liver, and lung cancers. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
