Product Data Sheet
Vasonatrin Peptide (VNP)
Catalog No. A84795
Vasonatrin Peptide (VNP) is a synthetic chimera that combines the properties of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). It exhibits vasorelaxing effects, including enhanced venodilation typical of CNP and natriuretic activity associated with ANP, along with unique arterial vasodilating effects. VNP has been shown to protect against ischemia-reperfusion injury in diabetic models by modulating ER stress through the cGMP-PKG signaling pathway, making it a valuable tool for cardiovascular research.
Chemical Information
| Catalog Num | A84795 |
|---|---|
| M. Wt | 2865.37 |
| Formula | C123H198N36O36S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 141676-35-9 |
| Synonyms | |
| SMILES | [C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(O)=O)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC(=O)[C@@H]3CSSC[C@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CC(C)C)=O)CO)=O)CCCCN)=O)=O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N3)[H])CC(N)=O)=O)CO)=O |
Biological Activity
| Description | Vasonatrin Peptide (VNP) is a synthetic chimera that combines the properties of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). It exhibits vasorelaxing effects, including enhanced venodilation typical of CNP and natriuretic activity associated with ANP, along with unique arterial vasodilating effects. VNP has been shown to protect against ischemia-reperfusion injury in diabetic models by modulating ER stress through the cGMP-PKG signaling pathway, making it a valuable tool for cardiovascular research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
