Product Data Sheet
AP-C7
Catalog No. A84801
AP-C7 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.0. This compound demonstrates weak inhibition of cGKII-dependent anion secretion, making it a valuable tool for exploring the role of cGKII in cellular signaling pathways and its impact on various physiological processes. AP-C7 can be utilized in research focused on cardiovascular biology, gastrointestinal function, and related areas studying cGMP signaling mechanisms.
Chemical Information
| Catalog Num | A84801 |
|---|---|
| M. Wt | 317.34 |
| Formula | C18H15N5O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2234275-84-2 |
| Synonyms | |
| SMILES | N1(C2=CC=C(C3=NC(NCC4=CC=CO4)=NC=C3)C=C2)C=CN=C1 |
Biological Activity
| Description | AP-C7 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.0. This compound demonstrates weak inhibition of cGKII-dependent anion secretion, making it a valuable tool for exploring the role of cGKII in cellular signaling pathways and its impact on various physiological processes. AP-C7 can be utilized in research focused on cardiovascular biology, gastrointestinal function, and related areas studying cGMP signaling mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
