Product Data Sheet

AP-C4

Catalog No. A84804

main product photo
AP-C4 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.2. This compound demonstrates the ability to effectively inhibit cGKII without affecting cGKII-dependent anion secretion. AP-C4 is valuable for research examining the role of cGKII in various physiological and pathological processes, enabling further exploration of cGKII's functions in signaling pathways.
Chemical Information
Catalog NumA84804
M. Wt372.42
FormulaC22H20N4O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.682794-85-0
Synonyms
SMILESC1(C2=CC3=C(OCCO3)C=C2)=NC(NCCC4=CNC5=C4C=CC=C5)=NC=C1
Biological Activity
DescriptionAP-C4 is a selective inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.2. This compound demonstrates the ability to effectively inhibit cGKII without affecting cGKII-dependent anion secretion. AP-C4 is valuable for research examining the role of cGKII in various physiological and pathological processes, enabling further exploration of cGKII's functions in signaling pathways.
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