Product Data Sheet

8-Br-PET-cGMP

Catalog No. A84806

main product photo
8-Br-PET-cGMP is a selective agonist of cGMP-dependent protein kinase type I (cGKI). It facilitates the dimerization of cGKI, enhancing its catalytic activity through binding to the regulatory domain. This compound is valuable for investigating cGMP signaling pathways involved in cellular processes such as growth, vasodilation, and the functionality of smooth muscle cells.
Chemical Information
Catalog NumA84806
M. Wt524.22
FormulaC18H15BrN5O7P
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.144510-04-3
Synonyms
SMILESO=C(N(C=C(C1=CC=CC=C1)N2)C2=N3)C4=C3N(C(Br)=N4)[C@H]5[C@H](O)[C@H](OP6(O)=O)[C@@H](CO6)O5
Biological Activity
Description8-Br-PET-cGMP is a selective agonist of cGMP-dependent protein kinase type I (cGKI). It facilitates the dimerization of cGKI, enhancing its catalytic activity through binding to the regulatory domain. This compound is valuable for investigating cGMP signaling pathways involved in cellular processes such as growth, vasodilation, and the functionality of smooth muscle cells.
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SHIPPING AND STORAGE
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