Product Data Sheet
PET-cGMP
Catalog No. A84807
PET-cGMP is a cyclic guanosine monophosphate analog that selectively activates protein kinase G (PKG) I, with an EC50 of 3.8 nM for the PKG Iβ isoform and 193 nM for PKG II. Its potent agonistic properties make it a valuable tool in studying signaling pathways involving PKG I, particularly in cardiovascular and neuronal research. Researchers can utilize PET-cGMP to elucidate the roles of cGMP signaling in various physiological and pathological contexts.
Chemical Information
| Catalog Num | A84807 |
|---|---|
| M. Wt | 445.32 |
| Formula | C18H16N5O7P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 78080-27-0 |
| Synonyms | |
| SMILES | O=C1C2=C(NC3=NC(C4=CC=CC=C4)=CN13)N([C@]5([H])O[C@@](CO[P]6(O)=O)([H])[C@](O6)([H])[C@H]5O)C=N2 |
Biological Activity
| Description | PET-cGMP is a cyclic guanosine monophosphate analog that selectively activates protein kinase G (PKG) I, with an EC50 of 3.8 nM for the PKG Iβ isoform and 193 nM for PKG II. Its potent agonistic properties make it a valuable tool in studying signaling pathways involving PKG I, particularly in cardiovascular and neuronal research. Researchers can utilize PET-cGMP to elucidate the roles of cGMP signaling in various physiological and pathological contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
