Product Data Sheet
SAG dihydrochloride
Catalog No. A84824
SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist, with an EC50 of 3 nM and a Kd of 59 nM. This compound effectively activates the Hedgehog signaling pathway, providing a robust mechanism to counteract the inhibitory effects of Cyclopamine. SAG dihydrochloride is valuable for research in developmental biology, cancer biology, and therapeutic strategies targeting Hedgehog-related pathways.
Chemical Information
| Catalog Num | A84824 |
|---|---|
| M. Wt | 562.98 |
| Formula | C28H30Cl3N3OS |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2702366-44-5 |
| Synonyms | |
| SMILES | O=C(C1=C(Cl)C2=CC=CC=C2S1)N([C@H]3CC[C@H](NC)CC3)CC4=CC=CC(C5=CC=NC=C5)=C4.[H]Cl.[H]Cl |
Biological Activity
| Description | SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist, with an EC50 of 3 nM and a Kd of 59 nM. This compound effectively activates the Hedgehog signaling pathway, providing a robust mechanism to counteract the inhibitory effects of Cyclopamine. SAG dihydrochloride is valuable for research in developmental biology, cancer biology, and therapeutic strategies targeting Hedgehog-related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
