Product Data Sheet
SMO-IN-1
Catalog No. A84837
SMO-IN-1 is an orally active Smoothened (SMO) inhibitor that demonstrates an EC50 of 89 nM for sonic hedgehog (Shh) protein. This compound is effective in disrupting the hedgehog signaling pathway, making it a valuable tool in cancer research and developmental biology studies. It may be particularly relevant for investigating tumors associated with aberrant hedgehog signaling.
Chemical Information
| Catalog Num | A84837 |
|---|---|
| M. Wt | 398.46 |
| Formula | C24H22N4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1126365-66-9 |
| Synonyms | |
| SMILES | CC1=CC=C(C=C1NC(C2=CC=C(C=C2)OCC3=NC=CC=C3)=O)C4=CN(C=N4)C |
Biological Activity
| Description | SMO-IN-1 is an orally active Smoothened (SMO) inhibitor that demonstrates an EC50 of 89 nM for sonic hedgehog (Shh) protein. This compound is effective in disrupting the hedgehog signaling pathway, making it a valuable tool in cancer research and developmental biology studies. It may be particularly relevant for investigating tumors associated with aberrant hedgehog signaling. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
