Product Data Sheet

SMO-IN-4

Catalog No. A84838

main product photo
SMO-IN-4 is a potent oral antagonist of the Smoothened (SMO) protein, displaying an IC50 of 24 nM. This compound demonstrates significant antitumor activity and is utilized in research focused on hedgehog signaling pathways and cancer therapy. SMO-IN-4 serves as a valuable tool for investigating SMO-related mechanisms in various malignancies.
Chemical Information
Catalog NumA84838
M. Wt450.96
FormulaC24H27ClN6O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1567963-99-8
Synonyms
SMILESClC1=CN=C(N2CC3=CN=C(N4CCC(CC4)O)N=C3CC2)C=C1C5=C(C)C=C(C)C=N5
Biological Activity
DescriptionSMO-IN-4 is a potent oral antagonist of the Smoothened (SMO) protein, displaying an IC50 of 24 nM. This compound demonstrates significant antitumor activity and is utilized in research focused on hedgehog signaling pathways and cancer therapy. SMO-IN-4 serves as a valuable tool for investigating SMO-related mechanisms in various malignancies.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.