Product Data Sheet

GW-6604

Catalog No. A84865

main product photo
GW-6604 is an inhibitor of ALK5, exhibiting an IC50 value of 140 nM for autophosphorylation inhibition. This compound serves as a valuable tool for investigating the molecular mechanisms associated with liver fibrosis. Its selective inhibition of ALK5 makes it relevant for research studies focused on fibrotic disease pathways and potential therapeutic interventions.
Chemical Information
Catalog NumA84865
M. Wt298.34
FormulaC19H14N4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.452342-37-9
Synonyms
SMILESC1(C2=NNC=C2C3=CC(C4=CC=CC=C4)=NC=C3)=CC=CC=N1
Biological Activity
DescriptionGW-6604 is an inhibitor of ALK5, exhibiting an IC50 value of 140 nM for autophosphorylation inhibition. This compound serves as a valuable tool for investigating the molecular mechanisms associated with liver fibrosis. Its selective inhibition of ALK5 makes it relevant for research studies focused on fibrotic disease pathways and potential therapeutic interventions.
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