Product Data Sheet

Chromenone 1

Catalog No. A84874

main product photo
Chromenone 1 is a potent enhancer of bone morphogenetic protein (BMP) signaling. It uniquely activates a pronounced, kinase-independent negative feedback mechanism on TGFβ, leading to an amplification of BMP-Smad signaling pathways within the nucleus. This compound is valuable for research into osteogenic differentiation and bone regeneration.
Chemical Information
Catalog NumA84874
M. Wt357.29
FormulaC18H10F3N3O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1639929-29-5
Synonyms
SMILESO=C1C(C2=CC=C(C(F)(F)F)C=C2)=C(N3N=CN=C3)OC4=CC=CC=C14
Biological Activity
DescriptionChromenone 1 is a potent enhancer of bone morphogenetic protein (BMP) signaling. It uniquely activates a pronounced, kinase-independent negative feedback mechanism on TGFβ, leading to an amplification of BMP-Smad signaling pathways within the nucleus. This compound is valuable for research into osteogenic differentiation and bone regeneration.
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SHIPPING AND STORAGE
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