Product Data Sheet
ALK5-IN-10
Catalog No. A84881
ALK5-IN-10 is a selective inhibitor of the TGF-β type I receptor kinase ALK5, exhibiting IC50 values of 0.007 μM for ALK5 and 1.98 μM for p38α. This compound demonstrates significant potential in modulating the TGF-β signaling pathway, making it a valuable tool for cancer research and therapeutic development. Its specificity for ALK5 allows for targeted investigations into tumorigenesis and associated pathways.
Chemical Information
| Catalog Num | A84881 |
|---|---|
| M. Wt | 460.33 |
| Formula | C22H18BrN7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1352608-94-6 |
| Synonyms | |
| SMILES | BrC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2 |
Biological Activity
| Description | ALK5-IN-10 is a selective inhibitor of the TGF-β type I receptor kinase ALK5, exhibiting IC50 values of 0.007 μM for ALK5 and 1.98 μM for p38α. This compound demonstrates significant potential in modulating the TGF-β signaling pathway, making it a valuable tool for cancer research and therapeutic development. Its specificity for ALK5 allows for targeted investigations into tumorigenesis and associated pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
