Product Data Sheet

ALK5-IN-25

Catalog No. A84899

main product photo
ALK5-IN-25 is a potent inhibitor of ALK-5 and ALK-2, exhibiting an IC50 of ≤10 nM. This compound interferes with TGF-β signaling pathways, making it a valuable tool for cancer research. ALK5-IN-25 is essential for studying the role of ALK-5 and ALK-2 in tumor progression and evaluating potential therapeutic strategies targeting these pathways.
Chemical Information
Catalog NumA84899
M. Wt430.48
FormulaC23H23FN8
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2785430-81-9
Synonyms
SMILESCC1=C(F)C=CC2=C(NC3=NC(NC4=CC=C(N5CCNCC5)C=C4)=NC=C3)C=NN=C12
Biological Activity
DescriptionALK5-IN-25 is a potent inhibitor of ALK-5 and ALK-2, exhibiting an IC50 of ≤10 nM. This compound interferes with TGF-β signaling pathways, making it a valuable tool for cancer research. ALK5-IN-25 is essential for studying the role of ALK-5 and ALK-2 in tumor progression and evaluating potential therapeutic strategies targeting these pathways.
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SHIPPING AND STORAGE
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