Product Data Sheet
BUR1
Catalog No. A84903
BUR1 is a bone morphogenetic protein (BMP) upregulator that primarily activates BMPRII signaling with an EC50 of 98 nM. It effectively induces the expression of BMP2 and PTGS2, making it a valuable tool in studies related to BMP signaling pathways. Additionally, BUR1 has been shown to reverse pulmonary arterial pressure in monocrotaline-induced rat models, highlighting its potential applications in cardiovascular and pulmonary research.
Chemical Information
| Catalog Num | A84903 |
|---|---|
| M. Wt | 279.34 |
| Formula | C16H17N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 23000-46-6 |
| Synonyms | |
| SMILES | C12=NC=NC(N3CCCCC3)=C1C=NN2C4=CC=CC=C4 |
Biological Activity
| Description | BUR1 is a bone morphogenetic protein (BMP) upregulator that primarily activates BMPRII signaling with an EC50 of 98 nM. It effectively induces the expression of BMP2 and PTGS2, making it a valuable tool in studies related to BMP signaling pathways. Additionally, BUR1 has been shown to reverse pulmonary arterial pressure in monocrotaline-induced rat models, highlighting its potential applications in cardiovascular and pulmonary research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
