Product Data Sheet
(Rac)-PF-998425
Catalog No. A84959
(Rac)-PF-998425 is a potent, selective nonsteroidal antagonist of the androgen receptor (AR). It exhibits IC50 values of 26 nM in AR binding assays and 90 nM in cellular assays, demonstrating significant efficacy in inhibiting AR activity. This compound is particularly relevant for research applications in androgenetic alopecia and related androgen-mediated conditions.
Chemical Information
| Catalog Num | A84959 |
|---|---|
| M. Wt | 269.26 |
| Formula | C14H14F3NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1076225-26-7 |
| Synonyms | |
| SMILES | OC1C(CCCC1)C2=CC(C(F)(F)F)=C(C=C2)C#N |
Biological Activity
| Description | (Rac)-PF-998425 is a potent, selective nonsteroidal antagonist of the androgen receptor (AR). It exhibits IC50 values of 26 nM in AR binding assays and 90 nM in cellular assays, demonstrating significant efficacy in inhibiting AR activity. This compound is particularly relevant for research applications in androgenetic alopecia and related androgen-mediated conditions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
