Product Data Sheet
Apalutamide-d4
Catalog No. A84960
Apalutamide-d4 is a deuterium-labeled derivative of Apalutamide, functioning as a potent competitive antagonist of the androgen receptor (AR). It demonstrates a binding affinity with an IC50 of 16 nM, making it valuable for studies involving androgen signaling pathways. This reagent is primarily used in research applications focused on prostate cancer and androgen-related disorders, facilitating the investigation of AR-mediated mechanisms and potential therapeutic strategies.
Chemical Information
| Catalog Num | A84960 |
|---|---|
| M. Wt | 481.46 |
| Formula | C21H11D4F4N5O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1638885-65-0 |
| Synonyms | ARN-509-d4 |
| SMILES | O=C(NC)C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F |
Biological Activity
| Description | Apalutamide-d4 is a deuterium-labeled derivative of Apalutamide, functioning as a potent competitive antagonist of the androgen receptor (AR). It demonstrates a binding affinity with an IC50 of 16 nM, making it valuable for studies involving androgen signaling pathways. This reagent is primarily used in research applications focused on prostate cancer and androgen-related disorders, facilitating the investigation of AR-mediated mechanisms and potential therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
