Product Data Sheet
AR antagonist 3
Catalog No. A84962
AR Antagonist 3 is a selective androgen receptor (AR) antagonist with a measured IC50 of 0.47 µM, demonstrating strong potency in blocking AR activity. It effectively reduces FRET signal in a dose-dependent manner, with an IC50 of 18.05 μM. In preclinical studies, AR Antagonist 3 has shown significant inhibition of tumor growth upon intratumoral administration, making it a valuable tool for research in androgen receptor-related cancer therapies.
Chemical Information
| Catalog Num | A84962 |
|---|---|
| M. Wt | 306.38 |
| Formula | C15H18N2O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 349573-58-6 |
| Synonyms | |
| SMILES | CN(S(=O)(NC1=CC=C(C=C1)OCC2=CC=CC=C2)=O)C |
Biological Activity
| Description | AR Antagonist 3 is a selective androgen receptor (AR) antagonist with a measured IC50 of 0.47 µM, demonstrating strong potency in blocking AR activity. It effectively reduces FRET signal in a dose-dependent manner, with an IC50 of 18.05 μM. In preclinical studies, AR Antagonist 3 has shown significant inhibition of tumor growth upon intratumoral administration, making it a valuable tool for research in androgen receptor-related cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
