Product Data Sheet
PF-998425
Catalog No. A84968
PF-998425 is a selective nonsteroidal androgen receptor (AR) antagonist, demonstrating significant potency with an IC50 of 37 nM in AR binding assays and 43 nM in cellular assays. This compound exhibits minimal activity towards common receptors and enzymes, such as the progesterone receptor. PF-998425 is relevant for research applications involving sebum control and the investigation of androgenetic alopecia.
Chemical Information
| Catalog Num | A84968 |
|---|---|
| M. Wt | 269.26 |
| Formula | C14H14F3NO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1076225-27-8 |
| Synonyms | |
| SMILES | O[C@H]1[C@H](CCCC1)C2=CC(C(F)(F)F)=C(C=C2)C#N |
Biological Activity
| Description | PF-998425 is a selective nonsteroidal androgen receptor (AR) antagonist, demonstrating significant potency with an IC50 of 37 nM in AR binding assays and 43 nM in cellular assays. This compound exhibits minimal activity towards common receptors and enzymes, such as the progesterone receptor. PF-998425 is relevant for research applications involving sebum control and the investigation of androgenetic alopecia. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
