Product Data Sheet
RD162
Catalog No. A84969
RD162 is a diarylthiohydantoin and a non-steroidal antiandrogen (NSAA) that exhibits selective binding to the androgen receptor (AR). This compound is notable for its ability to induce tumor regression in mouse models of castration-resistant human prostate cancer, highlighting its potential as a therapeutic agent in prostate cancer research. RD162 serves as a valuable tool for studying AR-targeted therapies and the mechanisms underlying castration resistance in prostate malignancies.
Chemical Information
| Catalog Num | A84969 |
|---|---|
| M. Wt | 476.45 |
| Formula | C22H16F4N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 915087-27-3 |
| Synonyms | |
| SMILES | O=C(NC)C1=CC=C(N(C(N(C2=CC=C(C#N)C(C(F)(F)F)=C2)C3=O)=S)C43CCC4)C=C1F |
Biological Activity
| Description | RD162 is a diarylthiohydantoin and a non-steroidal antiandrogen (NSAA) that exhibits selective binding to the androgen receptor (AR). This compound is notable for its ability to induce tumor regression in mouse models of castration-resistant human prostate cancer, highlighting its potential as a therapeutic agent in prostate cancer research. RD162 serves as a valuable tool for studying AR-targeted therapies and the mechanisms underlying castration resistance in prostate malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
