Product Data Sheet

N-Nitrosodicyclohexylamine

Catalog No. A84970

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N-Nitrosodicyclohexylamine (NDCHA) is an N-nitroso compound known for its anti-androgenic properties. It acts as a competitive antagonist of the androgen receptor (AR), effectively inhibiting the binding of 5α-dihydrotestosterone. Additionally, NDCHA reduces the protein levels of AR, making it a valuable tool for investigating androgen signaling pathways and potential therapeutic targets in androgen-related disorders.
Chemical Information
Catalog NumA84970
M. Wt210.32
FormulaC12H22N2O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.947-92-2
SynonymsNDCHA
SMILESO=NN(C1CCCCC1)C2CCCCC2
Biological Activity
DescriptionN-Nitrosodicyclohexylamine (NDCHA) is an N-nitroso compound known for its anti-androgenic properties. It acts as a competitive antagonist of the androgen receptor (AR), effectively inhibiting the binding of 5α-dihydrotestosterone. Additionally, NDCHA reduces the protein levels of AR, making it a valuable tool for investigating androgen signaling pathways and potential therapeutic targets in androgen-related disorders.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.