Product Data Sheet
HG122
Catalog No. A85013
HG122 is a selective compound that targets the androgen receptor (AR), promoting its degradation via the proteasome pathway. This mechanism inhibits the proliferation of castration-resistant prostate cancer cells, making HG122 a valuable tool for research in prostate cancer therapeutics and androgen signaling pathways. Its efficacy in disrupting AR signaling underscores its potential in studying therapeutic strategies for hormone-resistant cancers.
Chemical Information
| Catalog Num | A85013 |
|---|---|
| M. Wt | 343.29 |
| Formula | C15H13N5O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1854976-77-4 |
| Synonyms | |
| SMILES | O=C(NC1=CC2=NN(C3=CC=C(OC)C=C3)N=C2C=C1)CO[N+]([O-])=O |
Biological Activity
| Description | HG122 is a selective compound that targets the androgen receptor (AR), promoting its degradation via the proteasome pathway. This mechanism inhibits the proliferation of castration-resistant prostate cancer cells, making HG122 a valuable tool for research in prostate cancer therapeutics and androgen signaling pathways. Its efficacy in disrupting AR signaling underscores its potential in studying therapeutic strategies for hormone-resistant cancers. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
