Product Data Sheet
ERβ agonist-1
Catalog No. A85041
ERβ agonist-1 is a selective agonist for estrogen receptor beta (ERβ) with an EC50 of 46.8 nM, while also functioning as an androgen receptor (AR) antagonist with an IC50 of 1555 nM. This compound activates ERβ signaling through specific binding, simultaneously inhibiting AR activity. It is particularly valuable in research applications related to prostate cancer and demonstrates selective ERβ agonist effects in mouse models, supporting investigations into hormone-related pathologies.
Chemical Information
| Catalog Num | A85041 |
|---|---|
| M. Wt | 368.55 |
| Formula | C25H36O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2412715-30-9 |
| Synonyms | |
| SMILES | CC(CCC[C@]12C(C[C@H](C1)O)=C3CCC4=C(C(O)=CC=C4[C@]3(CC2)C)C)C |
Biological Activity
| Description | ERβ agonist-1 is a selective agonist for estrogen receptor beta (ERβ) with an EC50 of 46.8 nM, while also functioning as an androgen receptor (AR) antagonist with an IC50 of 1555 nM. This compound activates ERβ signaling through specific binding, simultaneously inhibiting AR activity. It is particularly valuable in research applications related to prostate cancer and demonstrates selective ERβ agonist effects in mouse models, supporting investigations into hormone-related pathologies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
