Product Data Sheet
ONC1-13B
Catalog No. A85061
ONC1-13B is a potent antagonist of the androgen receptor (AR), effectively inhibiting PSA expression in prostate cancer cells. This compound markedly reduces prostate cancer cell proliferation in the presence of dihydrotestosterone (DHT) stimulation. ONC1-13B exerts its anti-tumor effects by preventing androgen binding to AR and inhibiting its nuclear translocation, making it a valuable tool for prostate cancer research.
Chemical Information
| Catalog Num | A85061 |
|---|---|
| M. Wt | 492.45 |
| Formula | C22H16F4N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1351185-54-0 |
| Synonyms | |
| SMILES | O=C1[C@]2(CCOC2)N(C3=CC(F)=C(C=C3)C(NC)=O)C(N1C4=CC(C(F)(F)F)=C(C=C4)C#N)=S |
Biological Activity
| Description | ONC1-13B is a potent antagonist of the androgen receptor (AR), effectively inhibiting PSA expression in prostate cancer cells. This compound markedly reduces prostate cancer cell proliferation in the presence of dihydrotestosterone (DHT) stimulation. ONC1-13B exerts its anti-tumor effects by preventing androgen binding to AR and inhibiting its nuclear translocation, making it a valuable tool for prostate cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
