Product Data Sheet
G36
Catalog No. A85077
G36 is a cell-permeable antagonist of the G protein-coupled estrogen receptor GPER (GPR30). It selectively inhibits estrogen-induced activation of the PI3K pathway and effective calcium mobilization, with an IC50 value of 112 nM. G36 holds significant promise for research applications in cancer biology, particularly in studies focusing on estrogen signaling pathways and their implications in tumorigenesis.
Chemical Information
| Catalog Num | A85077 |
|---|---|
| M. Wt | 412.32 |
| Formula | C22H22BrNO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1392487-51-2 |
| Synonyms | |
| SMILES | CC(C1=CC2=C(N[C@@H](C3=C(Br)C=C(OCO4)C4=C3)[C@]5([H])[C@@]2([H])C=CC5)C=C1)C |
Biological Activity
| Description | G36 is a cell-permeable antagonist of the G protein-coupled estrogen receptor GPER (GPR30). It selectively inhibits estrogen-induced activation of the PI3K pathway and effective calcium mobilization, with an IC50 value of 112 nM. G36 holds significant promise for research applications in cancer biology, particularly in studies focusing on estrogen signaling pathways and their implications in tumorigenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
