Product Data Sheet
ERRα antagonist-1
Catalog No. A85082
ERRα antagonist-1 is a selective antagonist of estrogen-related receptor α (ERRα), effectively inhibiting its interaction with coactivators Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, with IC50 values of 170 nM and 180 nM, respectively. This compound is valuable for research applications focused on metabolic regulation and mitochondrial function, providing a tool for exploring ERRα's role in various physiological processes and disease states. ERRα antagonist-1 facilitates investigations into the therapeutic potential of targeting ERRα pathways in metabolic disorders and cancer.
Chemical Information
| Catalog Num | A85082 |
|---|---|
| M. Wt | 377.53 |
| Formula | C21H19N3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1072145-33-5 |
| Synonyms | |
| SMILES | C12=CC=CC=C1C(/N=C3SCCN\3C4=NCCS4)C5=CC=CC=C5C=C2 |
Biological Activity
| Description | ERRα antagonist-1 is a selective antagonist of estrogen-related receptor α (ERRα), effectively inhibiting its interaction with coactivators Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, with IC50 values of 170 nM and 180 nM, respectively. This compound is valuable for research applications focused on metabolic regulation and mitochondrial function, providing a tool for exploring ERRα's role in various physiological processes and disease states. ERRα antagonist-1 facilitates investigations into the therapeutic potential of targeting ERRα pathways in metabolic disorders and cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
