Product Data Sheet
β-Estradiol 17-acetate
Catalog No. A85088
β-Estradiol 17-acetate serves as an endogenous estrogen precursor, demonstrating significant cell viability and proliferation-enhancing properties. This compound promotes adhesion and proliferation in freshly isolated and revived female-derived human brain microvascular endothelial cells while reversing decreased viability in revived male-derived counterparts. β-Estradiol 17-acetate exhibits the microvascular protective effects of estrogen, facilitating the culture of non-tumor human brain microvascular endothelial cells in vitro for up to two months post-cryopreservation. In the human skin and other models, it is biotransformed into β-estradiol through hydrolase activity.
Chemical Information
| Catalog Num | A85088 |
|---|---|
| M. Wt | 314.42 |
| Formula | C20H26O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1743-60-8 |
| Synonyms | 1,3,5(10)-Estratriene-3,17β-diol 17-acetate |
| SMILES | C[C@@]1([C@H]2OC(C)=O)[C@](CC2)([H])[C@@](CCC3=C4C=CC(O)=C3)([H])[C@]4([H])CC1 |
Biological Activity
| Description | β-Estradiol 17-acetate serves as an endogenous estrogen precursor, demonstrating significant cell viability and proliferation-enhancing properties. This compound promotes adhesion and proliferation in freshly isolated and revived female-derived human brain microvascular endothelial cells while reversing decreased viability in revived male-derived counterparts. β-Estradiol 17-acetate exhibits the microvascular protective effects of estrogen, facilitating the culture of non-tumor human brain microvascular endothelial cells in vitro for up to two months post-cryopreservation. In the human skin and other models, it is biotransformed into β-estradiol through hydrolase activity. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
