Product Data Sheet
ERRα antagonist-2
Catalog No. A85137
ERRα antagonist-2 is an inverse agonist of the estrogen-related receptor alpha (ERRα), exhibiting an IC50 of 0.80 μM. This compound effectively inhibits the migration and invasion of the ER-negative MDA-MB-231 breast cancer cell line. Furthermore, ERRα antagonist-2 demonstrates the ability to suppress breast cancer growth in vivo, making it a valuable tool for research into breast cancer therapies and the role of ERRα in cancer progression.
Chemical Information
| Catalog Num | A85137 |
|---|---|
| M. Wt | 400.41 |
| Formula | C19H16N2O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3032965-02-6 |
| Synonyms | |
| SMILES | COC1=CC=C(C=C1)OC2=CC=CC=C2NS(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O |
Biological Activity
| Description | ERRα antagonist-2 is an inverse agonist of the estrogen-related receptor alpha (ERRα), exhibiting an IC50 of 0.80 μM. This compound effectively inhibits the migration and invasion of the ER-negative MDA-MB-231 breast cancer cell line. Furthermore, ERRα antagonist-2 demonstrates the ability to suppress breast cancer growth in vivo, making it a valuable tool for research into breast cancer therapies and the role of ERRα in cancer progression. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
