(R,R)-THC
Catalog No. A85156

(R,R)-THC is a selective estrogen receptor alpha (ERα) agonist and estrogen receptor beta (ERβ) antagonist, exhibiting Ki values of 9.0 nM for ERα and 3.6 nM for ERβ. This compound demonstrates higher binding affinity for ERβ than for ERα, with respective values of 25 nM and 3.6 nM. (R,R)-THC is valuable for research applications exploring estrogen receptor signaling pathways and investigating the differential roles of ERα and ERβ in various biological processes.
Chemical Information
| Catalog Num | A85156 |
|---|---|
| M. Wt | 320.42 |
| Formula | C22H24O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 221368-54-3 |
| Synonyms | |
| SMILES | OC(C=C1C[C@H]2CC)=CC=C1C3=C2C4=C(C=C(O)C=C4)C[C@H]3CC |
Biological Activity
| Description | (R,R)-THC is a selective estrogen receptor alpha (ERα) agonist and estrogen receptor beta (ERβ) antagonist, exhibiting Ki values of 9.0 nM for ERα and 3.6 nM for ERβ. This compound demonstrates higher binding affinity for ERβ than for ERα, with respective values of 25 nM and 3.6 nM. (R,R)-THC is valuable for research applications exploring estrogen receptor signaling pathways and investigating the differential roles of ERα and ERβ in various biological processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


