Product Data Sheet
EM-800
Catalog No. A85220
EM-800 is a potent antagonist of estrogen receptors α (ERα) and β (ERβ), exhibiting significant anti-estrogenic activity. This compound demonstrates anticancer properties by inhibiting the growth of breast cancer models induced by 7,12-Dimethylbenz[a]anthracene (DMBA). In ovariectomized animal studies, EM-800 effectively mitigates bone loss, presenting its utility in bone health research. Additionally, it offers valuable insights into breast and endometrial cancer studies, as well as potential benefits in lipid metabolism and overall metabolic health.
Chemical Information
| Catalog Num | A85220 |
|---|---|
| M. Wt | 625.79 |
| Formula | C39H47NO6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 182167-03-9 |
| Synonyms | |
| SMILES | CC(C)(C(OC1=CC2=C(C(C)=C([C@@H](O2)C3=CC=C(C=C3)OCCN4CCCCC4)C5=CC=C(C=C5)OC(C(C)(C)C)=O)C=C1)=O)C |
Biological Activity
| Description | EM-800 is a potent antagonist of estrogen receptors α (ERα) and β (ERβ), exhibiting significant anti-estrogenic activity. This compound demonstrates anticancer properties by inhibiting the growth of breast cancer models induced by 7,12-Dimethylbenz[a]anthracene (DMBA). In ovariectomized animal studies, EM-800 effectively mitigates bone loss, presenting its utility in bone health research. Additionally, it offers valuable insights into breast and endometrial cancer studies, as well as potential benefits in lipid metabolism and overall metabolic health. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
