Product Data Sheet
ERα degrader 13
Catalog No. A85224
ERα Degrader 13 is a potent degrader of estrogen receptor alpha (ERα) with an IC50 value of 0.55 μM. This compound effectively induces tumor regression in breast cancer xenograft mouse models, making it a valuable tool for studying ERα-related signaling and therapeutic approaches in breast cancer. Its targeted degradation mechanism provides insights into the role of ERα in cancer progression and treatment resistance.
Chemical Information
| Catalog Num | A85224 |
|---|---|
| M. Wt | 849.07 |
| Formula | C50H48N4O5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3070968-56-5 |
| Synonyms | |
| SMILES | CCN(C1=CC=C2N=C(C(SC2=C1)=C/C3=N/CCCCCCC(NCCOC4=CC=C(C=C4)C(C5=C(SC6=C5C=CC(O)=C6)C7=CC=C(C=C7)O)=O)=O)C8=C3C=CC=C8)CC |
Biological Activity
| Description | ERα Degrader 13 is a potent degrader of estrogen receptor alpha (ERα) with an IC50 value of 0.55 μM. This compound effectively induces tumor regression in breast cancer xenograft mouse models, making it a valuable tool for studying ERα-related signaling and therapeutic approaches in breast cancer. Its targeted degradation mechanism provides insights into the role of ERα in cancer progression and treatment resistance. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
