Product Data Sheet
CHF 4227 free base
Catalog No. A85235
CHF 4227 free base is a selective estrogen receptor modulator (SERM) that exhibits high affinity for both human estrogen receptor-α and -β, with Ki values of 0.017 nM and 0.099 nM, respectively. This compound demonstrates significant biological activity in modulating estrogen-related pathways, making it valuable for research in hormone-dependent tumors and other estrogen-related diseases. Its oral bioavailability allows for convenient administration in various preclinical studies.
Chemical Information
| Catalog Num | A85235 |
|---|---|
| M. Wt | 471.59 |
| Formula | C30H33NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 444643-64-5 |
| Synonyms | |
| SMILES | OC1=CC=C2C(CC3=CC=C(OCCN4CCCCC4)C=C3)=C(C5=CC=C(OC)C=C5)COC2=C1 |
Biological Activity
| Description | CHF 4227 free base is a selective estrogen receptor modulator (SERM) that exhibits high affinity for both human estrogen receptor-α and -β, with Ki values of 0.017 nM and 0.099 nM, respectively. This compound demonstrates significant biological activity in modulating estrogen-related pathways, making it valuable for research in hormone-dependent tumors and other estrogen-related diseases. Its oral bioavailability allows for convenient administration in various preclinical studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
