Product Data Sheet
Estrogen receptor modulator 11
Catalog No. A85246
Estrogen Receptor Modulator 11 is a tetrahydroisoquinoline derivative that selectively targets estrogen receptors (ER). It demonstrates affinity for both ERα and ERβ, with IC50 values of 285 nM and 421 nM, respectively. Notably, Estrogen Receptor Modulator 11 exhibits no antagonist activity in the MCF-7 cellular assay, indicating potential as a selective modulator in estrogen-related research applications. This compound is valuable for studies focused on ER signaling pathways and related therapeutic developments.
Chemical Information
| Catalog Num | A85246 |
|---|---|
| M. Wt | 319.37 |
| Formula | C21H18FNO |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 96719-63-0 |
| Synonyms | |
| SMILES | FC1=CC=C(C2C3=CC=C(C=C3CCN2C4=CC=CC=C4)O)C=C1 |
Biological Activity
| Description | Estrogen Receptor Modulator 11 is a tetrahydroisoquinoline derivative that selectively targets estrogen receptors (ER). It demonstrates affinity for both ERα and ERβ, with IC50 values of 285 nM and 421 nM, respectively. Notably, Estrogen Receptor Modulator 11 exhibits no antagonist activity in the MCF-7 cellular assay, indicating potential as a selective modulator in estrogen-related research applications. This compound is valuable for studies focused on ER signaling pathways and related therapeutic developments. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
