Product Data Sheet
Bazedoxifene-d4
Catalog No. A85248
Bazedoxifene-d4 is a deuterium-labeled analog of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM) that exhibits a potent affinity for estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound is utilized in research focused on osteoporosis and has been shown to inhibit IL-6/GP130 protein-protein interactions, making it relevant for studies related to pancreatic cancer. Its stable isotope labeling facilitates advanced metabolic and pharmacokinetic investigations.
Chemical Information
| Catalog Num | A85248 |
|---|---|
| M. Wt | 474.63 |
| Formula | C30H30D4N2O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1133695-49-4 |
| Synonyms | TSE-424-d4 |
| SMILES | CC1=C(N(C2=C1C=C(C=C2)O)CC3=CC=C(C=C3)OC([2H])(C([2H])(N4CCCCCC4)[2H])[2H])C5=CC=C(C=C5)O |
Biological Activity
| Description | Bazedoxifene-d4 is a deuterium-labeled analog of Bazedoxifene, a nonsteroidal selective estrogen receptor modulator (SERM) that exhibits a potent affinity for estrogen receptors ERα and ERβ, with IC50 values of 23 nM and 99 nM, respectively. This compound is utilized in research focused on osteoporosis and has been shown to inhibit IL-6/GP130 protein-protein interactions, making it relevant for studies related to pancreatic cancer. Its stable isotope labeling facilitates advanced metabolic and pharmacokinetic investigations. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
