Product Data Sheet
FSH receptor antagonist 1
Catalog No. A85249
FSH Receptor Antagonist 1 specifically targets the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor, functioning as a potent antagonist with an IC50 of 28 nM in cells expressing this receptor. This compound effectively inhibits follicle development and ovulation in ex vivo mouse models, making it valuable for research in reproductive biology and hormonal regulation. Its application in studying FSH signaling pathways provides insight into fertility-related processes and potential therapeutic interventions.
Chemical Information
| Catalog Num | A85249 |
|---|---|
| M. Wt | 488.62 |
| Formula | C33H32N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 487064-35-7 |
| Synonyms | |
| SMILES | O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C4C(C(C)(CC(C)(C)N4C(C)=O)C5=CC=CC=C5)=C3 |
Biological Activity
| Description | FSH Receptor Antagonist 1 specifically targets the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor, functioning as a potent antagonist with an IC50 of 28 nM in cells expressing this receptor. This compound effectively inhibits follicle development and ovulation in ex vivo mouse models, making it valuable for research in reproductive biology and hormonal regulation. Its application in studying FSH signaling pathways provides insight into fertility-related processes and potential therapeutic interventions. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
