Product Data Sheet
ERβ agonist-2
Catalog No. A85256
ERβ agonist-2 is a selective agonist for estrogen receptor beta (ERβ), exhibiting an EC50 of 800 nM or lower. It effectively inhibits T cell activation and proliferation, leading to a reduction in circulating T cell levels, while sparing neutrophils, monocytes, and B cells. This compound is relevant for research applications related to chronic heart failure post-myocardial infarction, as well as in studies of graft-versus-host disease, multiple sclerosis, and experimental autoimmune encephalomyelitis.
Chemical Information
| Catalog Num | A85256 |
|---|---|
| M. Wt | 304.34 |
| Formula | C19H16N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 628321-25-5 |
| Synonyms | |
| SMILES | OC1=CC=C(C2=C(C3=C(C)ON=C3C)NC4=C2C=CC=C4)C=C1 |
Biological Activity
| Description | ERβ agonist-2 is a selective agonist for estrogen receptor beta (ERβ), exhibiting an EC50 of 800 nM or lower. It effectively inhibits T cell activation and proliferation, leading to a reduction in circulating T cell levels, while sparing neutrophils, monocytes, and B cells. This compound is relevant for research applications related to chronic heart failure post-myocardial infarction, as well as in studies of graft-versus-host disease, multiple sclerosis, and experimental autoimmune encephalomyelitis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
