Product Data Sheet
PSDalpha
Catalog No. A85292
PSDalpha is an estrogen receptor alpha (ERα) degrader that features a conjugation of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol through an acetylene bond. It demonstrates potent anti-proliferative effects on MCF-7 breast cancer cells. PSDalpha exhibits a maximum absorption wavelength of 465 nm in the visible spectrum, making it suitable for photodynamic therapy applications and studies related to ERα-targeted cancer treatments.
Chemical Information
| Catalog Num | A85292 |
|---|---|
| M. Wt | 673.86 |
| Formula | C44H39N3O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2906869-08-5 |
| Synonyms | |
| SMILES | C[C@@]12[C@](CC[C@]2(O)C#CC3=CC=C(C4=CC=C(C=C4)N(C5=CC=CC=C5)C6=CC=CC=C6)C7=NSN=C37)([H])[C@@]8([H])[C@@](CC1)([H])C9=CC=C(O)C=C9CC8 |
Biological Activity
| Description | PSDalpha is an estrogen receptor alpha (ERα) degrader that features a conjugation of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol through an acetylene bond. It demonstrates potent anti-proliferative effects on MCF-7 breast cancer cells. PSDalpha exhibits a maximum absorption wavelength of 465 nm in the visible spectrum, making it suitable for photodynamic therapy applications and studies related to ERα-targeted cancer treatments. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
