Product Data Sheet

Estrogen receptor modulator 6

Catalog No. A85295

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Estrogen Receptor Modulator 6 is a selective agonist for Estrogen Receptor β, demonstrating a Ki value of 0.44 nM. With a 19-fold selectivity for ERβ over ERα (Ki = 8.4 nM), this compound enhances ERβ-mediated signaling, making it a valuable tool for studies in estrogen signaling pathways and related therapeutic research. Its selective action positions it as a potential candidate for investigating disorders influenced by estrogen receptor activity.
Chemical Information
Catalog NumA85295
M. Wt318.31
FormulaC18H16F2O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.787621-78-7
Synonyms
SMILESFC1(C[C@@]2([H])[C@](C1)([H])C3=CC(O)=CC=C3O[C@@]2([H])C4=CC=C(C=C4)O)F
Biological Activity
DescriptionEstrogen Receptor Modulator 6 is a selective agonist for Estrogen Receptor β, demonstrating a Ki value of 0.44 nM. With a 19-fold selectivity for ERβ over ERα (Ki = 8.4 nM), this compound enhances ERβ-mediated signaling, making it a valuable tool for studies in estrogen signaling pathways and related therapeutic research. Its selective action positions it as a potential candidate for investigating disorders influenced by estrogen receptor activity.
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