Product Data Sheet

TTC-352

Catalog No. A85308

main product photo
TTC-352 is an orally bioavailable selective partial agonist of the human estrogen receptor (ER) α, classified as a ShERPA. It effectively inhibits the proliferation of estrogen receptor-positive breast cancer cells, demonstrating significant antitumor activity. Additionally, TTC-352 promotes tumor regression by facilitating the translocation of ERα from the nucleus to extranuclear locations, making it a valuable tool for research in breast cancer therapeutics.
Chemical Information
Catalog NumA85308
M. Wt352.38
FormulaC20H13FO3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1607819-68-0
Synonyms
SMILESOC1=CC=C(C(C2=CC=C(F)C=C2)=C(OC3=CC=C(O)C=C3)S4)C4=C1
Biological Activity
DescriptionTTC-352 is an orally bioavailable selective partial agonist of the human estrogen receptor (ER) α, classified as a ShERPA. It effectively inhibits the proliferation of estrogen receptor-positive breast cancer cells, demonstrating significant antitumor activity. Additionally, TTC-352 promotes tumor regression by facilitating the translocation of ERα from the nucleus to extranuclear locations, making it a valuable tool for research in breast cancer therapeutics.
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