Product Data Sheet
17-Epiestriol
Catalog No. A85321
17-Epiestriol is an estrogen metabolite that acts as a selective estrogen receptor (ER) β agonist. It is known to inhibit the mRNA and protein expression of vascular cell adhesion molecule VCAM-1 induced by tumor necrosis factor α (TNFα), thereby preventing NF-κB migration to the nucleus. Additionally, 17-epiestriol promotes the expression of endothelial nitric oxide synthase at both mRNA and protein levels. This compound is useful in research related to vascular inflammation and endothelial function.
Chemical Information
| Catalog Num | A85321 |
|---|---|
| M. Wt | 288.38 |
| Formula | C18H24O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1228-72-4 |
| Synonyms | |
| SMILES | C[C@@]12[C@](C[C@H]([C@H]2O)O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4CC3 |
Biological Activity
| Description | 17-Epiestriol is an estrogen metabolite that acts as a selective estrogen receptor (ER) β agonist. It is known to inhibit the mRNA and protein expression of vascular cell adhesion molecule VCAM-1 induced by tumor necrosis factor α (TNFα), thereby preventing NF-κB migration to the nucleus. Additionally, 17-epiestriol promotes the expression of endothelial nitric oxide synthase at both mRNA and protein levels. This compound is useful in research related to vascular inflammation and endothelial function. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
