Product Data Sheet
Metahexestrol
Catalog No. A85324
Metahexestrol functions as an estrogen receptor (E2R) inhibitor, demonstrating significant antitumor activity. It effectively inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cells with an ED50 of 1.0 μM. Notably, Metahexestrol also shows inhibitory effects on estrogen receptor-negative MDA-MB-231 cells, indicating that its antiproliferative action may occur independently of the E2R pathway. This compound is valuable for research focused on estrogen-dependent breast cancer.
Chemical Information
| Catalog Num | A85324 |
|---|---|
| M. Wt | 270.37 |
| Formula | C18H22O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 71953-72-5 |
| Synonyms | |
| SMILES | CC[C@H](C1=CC(O)=CC=C1)[C@H](C2=CC(O)=CC=C2)CC |
Biological Activity
| Description | Metahexestrol functions as an estrogen receptor (E2R) inhibitor, demonstrating significant antitumor activity. It effectively inhibits the proliferation of estrogen receptor-positive MCF-7 human breast cancer cells with an ED50 of 1.0 μM. Notably, Metahexestrol also shows inhibitory effects on estrogen receptor-negative MDA-MB-231 cells, indicating that its antiproliferative action may occur independently of the E2R pathway. This compound is valuable for research focused on estrogen-dependent breast cancer. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
