Product Data Sheet
LY2066948
Catalog No. A85325
LY2066948 is a selective estrogen receptor modulator (SERM) that exhibits high affinity for estrogen receptors ERα and ERβ, with Ki values of 0.51 nM and 1.36 nM, respectively. This compound demonstrates potent antiestrogenic activity, effectively blocking uterine weight gain induced by Ethynyl estradiol in immature rats. LY2066948 is employed in research related to uterine fibroids and myomas, contributing to the understanding of estrogen-related pathologies.
Chemical Information
| Catalog Num | A85325 |
|---|---|
| M. Wt | 517.64 |
| Formula | C30H31NO5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 648904-56-7 |
| Synonyms | |
| SMILES | OC1=CC=C2C(OC3=CC=C(C=C3)OCCN4CCCCC4)=C(C=CC2=C1)C5=CC=C(C=C5)S(=O)(C)=O |
Biological Activity
| Description | LY2066948 is a selective estrogen receptor modulator (SERM) that exhibits high affinity for estrogen receptors ERα and ERβ, with Ki values of 0.51 nM and 1.36 nM, respectively. This compound demonstrates potent antiestrogenic activity, effectively blocking uterine weight gain induced by Ethynyl estradiol in immature rats. LY2066948 is employed in research related to uterine fibroids and myomas, contributing to the understanding of estrogen-related pathologies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
